ATG3 anticorps (Middle Region)

N° du produit ABIN497989

Cet anticorps Lapin Polyclonal détecte spécifiquement ATG3 dans WB et EIA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ATG3 anticorps (Middle Region) (ABIN497989)

Antigène: ATG3 (ATG3 Autophagy Related 3 (ATG3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-ATG3 anticorps

Épitope: Middle Region

Purification: Immunoaffinity Chromatography

Immunogène: ATG3 antibody was raised against an 18 amino acid peptide near the center of Human ATG3 (GenBank accession no. NP_071933).

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: ATG3 antibody can be used for the detection of ATG3 at 1-2 μg/mL. Positive Control: Mouse Kidney Tissue Lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur ATG3

Antigène: ATG3 (ATG3 Autophagy Related 3 (ATG3))

Autre désignation: APG3 / ATG3

Sujet: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG3 (APG3) is a widely expressed conjugating enzyme for APG8 lipidation, an essential step for the initiation of autophagy. It functions as an E2-like enzyme during the initial stages of autophagosome formation by catalyzing the formation of the Atg8-phosphatidylethanolamine (Atg8-PE) conjugate, which is critical for autophagy.Synonyms: APG3-like, APG3L, Autophagy-related protein 3, Protein PC3-96

ID gène: 64422

NCBI Accession: NP_071933

UniProt: Q9NT62

Pathways: Autophagy